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If the induction of anaplerosis through pyruvate carboxylation is a compensatory mechanism to maintain Krebs cycle moieties, 17 early supplementation with an anaplerotic substrate may allow pyruvate to be oxidized by PDH

Association of BDNF Val66Met polymorphism and brain BDNF levels with major depression and suicide

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Reducing Treatment-Related Side Effects: CoQ10 and L-carnitine may help reduce treatment-related side effects, such as fatigue, nausea, and vomiting
