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Studies on the individual components have explored their roles in cell migration, growth factor signaling, oxidative stress responses, and gene expression modulation

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Each element of the blood transport mechanism to the heart, when failing, sequentially causes blood stasis in the veins, the development of inflammation, damage to the endothelial layer lining the vessel, subsequently forming a thrombus that prevents blood transport to the heart

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Inositol plays roles in cell signalling and lipid metabolism, though its direct lipotropic effects in humans remain poorly characterised