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Gastrointestinal reactions may result from a too rapid consumption of carnitine

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Acylcarnitine profile In primary carnitine deficiency the transport of carnitine over the plasma membrane is impaired resulting in low intracellular carnitine concentrations

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Consistently, the Princeton III Consensus Recommendations for the management of ED and CVD indicate that incident ED has a similar or even greater predictive value for CVD, when compared to traditional risk factors exerting a direct detrimental impact on the endothelial function [13]

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