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Description
856 treatment of eosinophilic esophagitis with the CRTH2-antagonist Oc000459: a novel therapeutic principle

During hypoxia or under certain oncogenic conditions, -ketoglutarate could be converted directly to citrate (following a reversed TCA cycle), in order to generate the cytosolic acetyl-CoA when glucose-derived acetyl-CoA is insufficient [34]
Significantly, several Pt nanozyme-based formulations have already been approved for clinical use or are currently under clinical investigation (Table S2)

Acknowledgments We thank all contributing authors and reviewers for their work and dedication to this review

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