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Tumors and major organs including heart, liver, spleen, lung, and kidney were isolated

Among MSI CRCs, the fraction of isolated PMS2 loss varies between 1% and 8%, with more than half of these tumors being linked to germline pathogenic PMS2 variants

doi: 10.3389/fimmu.2021.666223

[DOI] [PubMed] [Google Scholar] 62.Barker RA, Studer L, Cattaneo E, et al