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The resulting accumulation of lipid ROS, coupled with the ability of ONOO to directly initiate lipid peroxidation, creates a vicious cycle of membrane damage
Cancer cells typically exhibit elevated basal ROS levels due to increased metabolic activity, mitochondrial dysfunction, and oncogene activation
[DOI] [PubMed] [Google Scholar] 15
A peptide that is 85% pure might be acceptable for some research contexts
To better explore the differences between G3PDH enzymes, we used phylogenetic analyses of representative FAD-dependent G3PDH sequences across all domains of life, including Archaea, Bacteria and Eukarya
