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3.4 Connections between genetic mutations and metabolic changes The HPGL/PCC syndrome, where loss-of-function mutations affect SDH and increase intracellular levels of the oncometabolite succinate, thus causing onset of pheochromocytoma and paraganglioma, is a proof-of-concept that metabolic changes can drive tumorigenesis
[DOI] [PubMed] [Google Scholar] 152.Bremelanotide Approval Letter
Braakhuis et al
Koprich, J
Huyt thanh trng da dng bi Glutathione Ampoule 551 c kim chng v an ton, yn tm khi s dng
