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In vivo murine studies further support their use, revealing superior tissue integration and structural support during regeneration [140]
166 The effect may be mediated by the activation of autophagy 165 through the PI3K/Akt pathway 167 or AMPK/SIRT1 signaling pathway 168 but does not seem to involve the MAP kinase pathways or the NF-B/SIRT1 pathway
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Fibers are far enough apart to leave ample open space for interstitial fluid in between
As a diradical, O 2 readily reacts rapidly with other radicals
