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As the importance of myelination for neuronal physiology cannot be overstated, it is surprising that the neuronal replacement field has developed with little attention to this important aspect
The domain of G0S2 which inhibits PNPLA2 comprises amino acids K20-A52 and does not inhibit the function of other PNPLA family members PNPLA6 and 7, or HSL, MGL, and lipoprotein lipase (54)
Avoid vigorous shaking during reconstitution, minimize moisture exposure of the lyophilized vial, protect the vial from light, and avoid repeated freeze-thaw cycles
