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These results confirm that proline at position 3 (P3) is a critical residue for BPC157-mediated endothelial cell proliferation

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FPN is the only known transmembrane iron exporter in vertebrates, primarily expressed in duodenal enterocytes, hepatocytes, and macrophages, where it plays a crucial role in maintaining cellular and systemic iron homeostasis (39)

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In some cases, Beau's lines may gradually disappear on their own as the nail grows out

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Deficiency causes mucocutaneous bleeding and characteristically shows an abnormal ristocetin cofactor assay, as ristocetin requires vWF to induce platelet agglutination

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