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Es aktiviert auch die Produktion von Matrix-Metalloproteinasen (MMP-2), die am Gewebeumbau beteiligt sind, whrend es bermige pro-inflammatorische MMPs hemmt

Some studies report modest increases in lean mass (1-3 kg over 6 months), while others show maintenance of lean mass rather than significant gains

Nutrients 2019;11

Niacin therapy increases high-density lipoprotein particles and total cholesterol efflux capacity but not ABCA1-specific cholesterol efflux in statin-treated subjects

this may interfere with nutrient absorption functions, thereby altering the quantity or location of the bacterial food matrix and disrupting the intestinal flora (Epstein et al., 2006)