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Additionally, mitochondrial ROS-induced oxidation of GSDMD is a crucial mechanism facilitating GSDMD cleavage, which in turn drives NLRP3-dependent pyroptosis in macrophage [144]
Interestingly, this promising technology was adapted later to prepare a CD-based rotaxane as a near infrared-triggered drug release for in vivo evaluation 57
Nerolidol Nerolidol is a sesquiterpene compound having promising antioxidant and anti-inflammatory properties [85, 86]
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