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Furthermore, the therapeutic implications of SAMe are promising, with evidence suggesting that SAMe supplementation or modulation could improve the efficacy of existing cancer treatments by restoring proper methylation patterns and mitigating oxidative damage and protect against damage induced by chemotherapeutic drugs

Risk of cancer in patients treated with human pituitary growth hormone in the UK, 1959-85: a cohort study

Furthermore, apart from the cancer cell itself, the gut microbiota, including bacteria and viruses, has been implicated in playing a vital role in tumorigenesis and impacting the therapeutic efficacies of cancer patients, especially GI patients

Blood 140 (5): 451-463, 2022

Goldberg, D