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Helps the body convert stored fat into usable energy

Figure 2 Genetic Regulation APOE Expression Through the PPAR-LXR-ApoE System The genetic control of APOE expression differs by cell type and is tightly linked to the lipid loading of cells (Laffitte et al., APOE gene expression with inflammatory and cellular energy utilization preferences

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The mean liver weight increased with age in both sexes in all HFD-treated groups, with subjects at 40 weeks of age exhibiting a significantly higher liver weight than those in the intact group

Weight of evidence: Overall evidence is Moderate : pediatric trials show lipid-peroxidation reduction and improved antioxidant status, with mixed behavioral effects