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They are not a replacement for evidence-based care

doi:10.1111/j.1432-1033.1997.00273.x

Cent Nerv Syst Agents Med Chem 19(3):154170

Your stomach acid, liver enzymes, and intestinal barriers all take their toll, breaking down much of the NAD+ before it ever reaches your cells
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Avoid hot drinks until temperature perception normalizes
