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Photodynamic therapy: one step ahead with self-assembled nanoparticles

A self-made extracellular matrix that frequently consists of exopolysaccharides, amyloid fibers, secreted proteins, and extracellular DNA holds biofilms together and serves as their protective covering (Erskine et al., 2018)

& Yudkoff, M

Once released, mtDNA can be internalized into endolysosomal compartments through processes like phagocytosis, autophagy, or uptake of EVs [125, 126])

Approximately 20% of cases may feature spread to lungs or lymph nodes