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Naik M (2024) Synthesis of ZnO nanoparticles using Mussaenda frondose and its Applications in Sensor with Antibacterial Studies 119 Lima EBC, Sousa CNS, Meneses LN, Ximenes NC, Jnior S, Vasconcelos GS, Lima NBC, Patrocnio MCA, Macedo D, Vasconcelos SMM (2015) Cocos nucifera (L)(Arecaceae): a phytochemical and pharmacological review

Hydroxyproline metabolism and oxalate synthesis in primary hyperoxaluria
demonstrated that inoculation of pathogenic -syn preformed fibrils into the gut of aged mice resulted in a marked increase of -syn in the brainstem and the emergence of pathological changes in the central nervous system [38]

Later, in 1597, John Gerard recognised it as one of the most effective remedies for depressive disorders