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The most likely explanation is that somewhere between 0% and 20% is needed to maintain basic functions so that larger amounts are not needed under benign laboratory conditions

3 Endocrine dysfunction, including goiter, hypothyroidism, and calcium metabolism abnormalities, has occasionally been documented

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Employing non-hydroxylated vitamin D forms that are effectively maintained in conjunction with the bodys self-regulation of vitamin D activation may help minimize the risk of toxicity (Pludowski et al., 2018)

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