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In the mouse DG, new neurons differentially modulate different inputs from both lateral and medial entorhinal cortex, which have profound influence on DG normal physiology (Luna et al., 2019)

Thus, MOTS-c appears to promote osteoblasts to synthesize type I collagen via this pathway

Ling, M.B

References 1.Perovic D., Kolenc D., Bilic V., Somun N., Drmic D., Elabjer E., Buljat G., Seiwerth S., Sikiric P

While effective, this conventional method often faced constraints such as the difficulty of perfectly aligning hardware with a patients unique anatomy with off-the-shelf implants, and the physical toll of harvesting a patients own bone for graft in certain cases