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Unfortunately, many people dont get enough B12 through diet alone, leading to deficiencies that can cause fatigue, mood swings, and even more serious health issues

Specifically, the effect allele encodes for leucine, which is more hydrophobic than the reference proline allele and may therefore increase stability of the hydrophobic region of the signal peptide (Supplementary Information)

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Haahtela T, Holgate S, Pawankar R, Akdis CA, Benjaponpitak S, Caraballo L, Demain J, Portnoy J, von Hertzen L, WAO Special Committee on Climate Change and Biodiversity

Wu W, Chen X, Hu C, Li J, Yu Z, Cai W (2010) Transplantation of neural stem cells expressing hypoxia-inducible factor-1 (HIF-1) improves behavioral recovery in a rat stroke model