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Elevated copper in Alzheimers disease has also been widely reported 42 , although evidence exists to show that while elevated copper is associated with plaques 43 , brain copper levels more broadly are decreased 44,45 and improving copper bioavailability can ameliorate pathology in a mouse model of disease 46,47

Using multi-omic and bioenergetics analyses, a recent study demonstrated that high-OXPHOS ovarian cancer cells with higher ROS content exhibited greater sensitivity to taxane and platinum treatment compared to low-OXPHOS cells [58]

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