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Some patients, particularly those with neurological involvement, may benefit from more frequent dosing (every 2 months rather than 3 months), but this should be medically supervised rather than self-adjusted

Vitamin B12 supplements are generally safe because excess vitamin B12 is excreted in your urine

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For optimal results within a research setting, please adhere to standard laboratory protocols for reconstitution using bacteriostatic water or research-grade solvent appropriate for each compound

High-dose oral methylcobalamin is well absorbed in most and more convenient long-term