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In addition, it has been demonstrated that ROS are also actively involved in the formation of NETs [109], autophagy [110,111,112], chemoattraction and activation of the inflammasome [113,114,115], programmed cell death of infected reservoirs [116, 117], antigen presentation, T-helper cell activation and lymphocyte proliferation [118,119,120,121]

however, this population is heterogeneous and may utilize distinct aspects of the available mitochondrial metabolism for maintenance and function

G6PD is the major source of the cytosolic NADPH pool (see the Metabolic Sources and Cellular Distribution of the NAD(H) and NADP(H) Couples section)

albicans challenge

Susanti D, Ruslan FS, Shukor MI, Nor NM, Aminudin NI, Taher M, Khotib J