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Preclinical research demonstrated that NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% , shrank adipocyte size by 30-40%, and lowered plasma cholesterol by ~30% all without affecting food intake
Boosting NAD level suppresses inflammatory activation of PBMCs in heart failure
doi: 10.1073/pnas.1604285113
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10.1097/ICO.0b013e31821dd986 143 TurkovicB.SikiricP.SeiwerthS.MiseS.AnicT.PetekM.et al (2004)
