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But, as NAD+ levels decline with age, its important to keep them topped up

A small molecule or peptide inhibitor of the Keap1/Nrf2 protein interaction may increase target selectivity and overcome toxicity and remains an attractive target [98]

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The tumor-targeted CD40 agonist CEA-CD40 promotes T cell priming via a dual mode of action by increasing antigen delivery to dendritic cells and enhancing their activation