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Preferential expression of IGF-I in small DRG neurons and down-regulation following injury

CJC-1295 is a 30-amino-acid peptide

Nox1 in cardiovascular diseases: regulation and pathophysiology

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The truncation reduces IGFBP binding similar to the LR3 modification, but DES IGF-1 retains a much shorter circulating half-life (typically reported in the 20 to 30 minute range) because the rest of the molecule remains susceptible to standard proteolytic clearance