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Chronic exposure to aluminum and melatonin through the diet: Neurobehavioral effects in a transgenic mouse model of Alzheimer disease

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These results suggest that chronic administration of melatonin was able to reduce the increase in inflammation, apoptosis, and oxidative stress related to age, especially in the group of animals with a higher degree of cardiovascular alterations (Figure 2)

Peptide therapy is only as good as the medical framework supporting it

This means, the presence of both mutated COMT and mutated MTHFR genes, together, may worsen the problem