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Patients were dialyzed for 45 h with high-flux dialyzers three times a week
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Treatment of functional mitral regurgitation in chronic heart failure: can we get a proof of concept from the MITRA-FR and COAPT trials

Additionally, apoE4 accelerates the degradation of the BBB through activation of the cyclophilin A-matrix metalloproteinase-9 (MMP9) pathway in pericytes, whereas suppression of this pathway improves BBB integrity and prevent apoE4-mediated behavioral deficits in amyloid mouse models [162]

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