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The 15-Lipoxygenase-1 Product 13-S-Hydroxyoctadecadienoic Acid down-Regulates PPAR- to Induce Apoptosis in Colorectal Cancer Cells
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574,575 Anti-inflammatory effects were also demonstrated for 13-HOTrE and the corresponding hydroperoxide 13-HpOTrE, with both compounds decreasing pro-inflammatory cytokine/enzyme levels while simultaneously increasing anti-inflammatory cytokines in LPS-challenged RAW 264.7 and mouse peritoneal macrophages
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