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Furthermore, membrane permeant inhibitor of MLCK (PIK), which reverses MLC phosphorylation, mitigates tumor necrosis factor alpha (TNF)-induced decreases in transepithelial resistance in cell culture and protects against gut damage in a model of binge ethanol exposure and burn injury [55, 56]

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Sox2 is expressed in both radial and horizontal NSCs and play a key role in NSC self-renewal [60, 70]
