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For example, if the goal is tendon recovery, a good plan often includes: Load management, sometimes more than people want to admit Physical therapy style strengthening and mobility work Protein adequacy and targeted nutrients Inflammation reduction strategies that do not sabotage healing Addressing sleep and stress Considering supportive therapies only when the foundation is in place That last point ties into the broader concept of functional medicine

The involvement of oxidative stress in the migraine pathophysiology has been discussed for decades

Reduced NAD+ levels impair mitochondrial function, leading to decreased ATP production and increased reactive oxygen species generation

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10.1016/j.mce.2017.11.002 152 RizzoA.RoscinoM