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Description
The net result of increased activation of this pathway is an alveolar epithelium that is already dysfunctional and thus primed for developing ARDS when faced with an acute insult
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During the ferroptotic activation process, elevated LAMP2A levels and HSP90-dependent CMA induction mediate GPX4 degradation (82)
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Preventing these with antibiotics and vaccination is one of the key preventative strategies for ECOPD
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Cell 160 , 729744 (2015)
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At the same time, ROS levels keep rising steadily
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