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The severity also varies, depending on the type of mutation and the extent of enzyme activity defects

NICE guidelines recommend evidence-based interventions including dietary modification, physical activity, and approved medications for weight management

Gastrointestinal disorders Less frequent: Gastrointestinal complaints, such as nausea, vomiting, diarrhoea and abdominal pain

This oral spray facilitates rapid, efficient absorption of Vitamin B12 directly into the bloodstream, bypassing the digestive system for quicker and more effective uptake, making it particularly beneficial for older adults, vegetarians, and those with certain digestive disorders

While some patients receive these shots at a clinic, many are advised by their healthcare providers to self-inject at home for convenience and consistency