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For the vehicle control group and the maximum LDH release control group, 180 l fresh culture medium and 20 l of sterile water were added

AST inhibits the activation of nuclear factor kappa-B (NF-B) and its translocation to the nucleus, reducing the transcription of pro-inflammatory factors such as TNF-, IL-1, and IL-6, and plays an anti-inflammatory role in conditions like arthritis, hepatitis, and pulmonary inflammation

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also show that MOTS-c administration also prevents ovariectomy-induced obesity and insulin resistance in mice via the AMPK pathway