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Thiols are extremely efficient antioxidants which can protect cellular lipids, proteins

In this essay, we review the recent progress in the understanding of the mechanism underlying cuproptosis, revisit the roles of p53 in metabolic regulation and iron-sulfur cluster and glutathione biosynthesis, and propose several potential mechanisms for wild-type and mutant p53-mediated cuproptosis regulation.

Programmed cell death is pivotal for several physiological processes, including immune defense

Brain GSH overall did not differ in AD or MCI compared to HC

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