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Day 1: 500mg NAD IV (1.5-3hrs) Day 4: 100mg NAD SQ Day 6: 100mg NAD SQ Daily: 250mg NR/NMN in the morning Week 7 We round off our loading phase with a large IV dose of NAD+, getting your body to optimal levels that we maintain throughout the rest of the cycle

For example, individuals with gastrointestinal issues may find injections more beneficial, as they ensure the vitamin bypasses the digestive system entirely

337 Additionally, fibroblast growth factor 21 mitigates liver fibrosis and injury induced by iron overload by preventing ferroptosis in hepatocytes

However, strengths of the study include the community-based recruitment, the unmedicated and mostly medication-nave MDD group, and the relatively large control sample that matched MDD cases in terms of education and other sociodemographic variables [7]