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Description
They typically cost between $5 and $15 and last for months of weekly injections

Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain

The same approach is being applied to AxD patients in an ongoing phase 13 clinical study (Zilganersen, NCT04849741

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Comprehensive preclinical safety evaluations across multiple animal models demonstrate favorable tolerability profiles with excellent safety margins for investigational research applications
