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Levels may drop as a result of oxidative stress due to disease, drugs, aging, toxic chemicals, inflammation, and stress in general
J Clin Hepatol
10.1016/j.jmb.2019.06.032 J
In addition to enhancing antioxidant defense, DMF has been reported to modulate inflammatory signaling, immune-cell activation, and cellular metabolism through mechanisms that are at least partially independent of NRF2 (Schulze-Topphoff et al., 2016
