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In neurons, DISC1 acts as a scaffolding protein and associates with a great number of synapse- and microtubule-associated proteins during cortical development and adulthood (Brandon and Sawa, 2010) demonstrated that knockdown of DISC1 in cultured rat cortical neurons leads to spine shrinkage
124,125 Key diagnostic approaches include gastric emptying scintigraphy, the 13C-octanoic acid breath test, wireless motility capsule for gastroparesis, and esophageal manometry with pH monitoring for esophageal dysmotility
Syngelaki et al
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In first-episode psychosis, Schwarz et al
