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Proceedings of the National Academy of Sciences of the United States of America 2019;116, 22624-22634, doi:10.1073/pnas.1915905116

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Recommended Testing Schedule Heres a suggested testing plan for B12 treatment: First test B12 levels before starting treatment Check again after the first dose (usually 1-3 months later) Test every 3-6 months while taking maintenance doses Test more often if you have trouble absorbing B12 or other health issues Interpreting B12 Levels During Treatment When looking at B12 levels, doctors must think about a few things