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doi: 10.1038/nm.2208
Recent imaging studies reveal that BBB breakdown and glymphatic system impairment associated with gliosis occur early in aging, particularly in the hippocampus, and are exacerbated in mild cognitive impairment, correlating with pericyte injury (Montagne et al., 2015)
Dihexa(PNB-0408), an oligopeptide drug, is an orally active and blood-brain barrier-permeable analog of angiotensin IV
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