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The kinetics of metabolism were slower in the organoids, where we observed phase I metabolism of heroin by CES to morphine in approximately 6 hours, while the controls produced morphine in approximately 12 minutes

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Dieses Phnomen kann die Folge von berdosierung, verringerten Plasmakonzentrationen gleichzeitig verabreichter Antiepileptika, Fortschreiten der Erkrankung oder ein paradoxer Effekt sein