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The randomness in the assignment of participants to treatments reduces selection bias and allocation bias, balancing both known and unknown prognostic factors, in the assignment of treatments

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Activation of the Nrf2 signaling pathway in A549 and human bronchial epithelial (HBE) cell lines further enhanced Tan IIAs antifibrotic effects by modulating EMT and TGF-1/Smad pathway activation ( Sorbus aucuparia , exhibits synergistic effects with Tan IIA in combating fibrosis progression (Xue et al., 2021)

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