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Melatonin is an antioxidant, anti-inflammatory, free radical scavenger, circadian rhythm regulator, and sleep hormone

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Corley MJ, Pang APS, Shikuma CM, Ndhlovu LC

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ROS induced lipid peroxidation and their role in ferroptosis

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GPX3, a key member of the GPX family, has predominantly been investigated within oncology [23,24,25], but it has also been shown to play essential roles in pathological processes such as inflammation, fibrosis, metabolic homeostasis and insulin resistance [26,27,28]

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Sulfonic acid (Cys36-SOH) is produced when peroxides directly oxidize Gpx3s catalytic Cys36

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