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Description
Unlike other organelles such as mitochondria, where an abundance of reduced glutathione (GSH) preserves a reductive environment, the ER requires an oxidizing milieu to facilitate the formation of disulfide bonds critical for protein structural integrity
[81] Surgical case series have shown low operative mortality rate (less than 2%) and improvement of symptoms in the majority of patients selected to receive surgery

doi: 10.1080/23312025.2016.1229086
INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway

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