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Caffeine is a widely used ingredient that may help support focus and energy levels as part of a pre-workout routine

Cell Metab 11:253256 Galmozzi A, Sonne SB, Altshuler-Keylin S, Hasegawa Y, Shinoda K, Luijten IHN, Chang JW, Sharp LZ, Cravatt BF, Saez E et al (2014) ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue
The biochemical half-lives suggest alternating provides more consistent metabolic support

These modifications produce a smaller, more potent compound that resists enzymatic degradation
