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Subcutaneous adipose tissue diseases: Dercum disease, lipedema, and Madelung disease

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Intriguingly, patients with liver metastasis showed significantly less CD8 + T cell infiltration into the tumor compared with those without liver metastasis 32 , suggesting VEGF-mediated T cell exclusion within tumors and explaining the attenuated response to anti-PD-1 therapy in VEGF-high tumors

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