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(2011) Insights into the evolution of vitamin B12 auxotrophy from sequenced algal genomes

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This damage can take the form of oxidized lipids, protein oxidation, or damage to DNA which causes cell death.[ref] In addition to being essential for energy production, mitochondria produce ROS and also play an important role in maintaining the right levels of ROS

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Imbalanced apoptosis and proliferation across major pulmonary vascular cell types, particularly pulmonary arterial endothelial cells (PAECs) and smooth muscle cells (PASMCs), are central to disease progression, exhibiting paradoxical effects that contribute to its complexity
