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Description
Laboratory studies demonstrate that ES2 peptides show 3-7 times more potent senolytic activity than FOXO4-DRI in both in vitro and in vivo experimental systems, while CPP-CAND demonstrates approximately 1.2-fold higher selectivity despite shorter peptide length
[DOI] [PubMed] [Google Scholar] 296.Jager H., Grissmer S
Eur J Pharmacol 737:106116 Brosius FC, Alpers CE, Bottinger EP, Breyer MD, Coffman TM, Gurley SB, Harris RC, Kakoki M, Kretzler M, Leiter EH (2009) Mouse models of diabetic nephropathy
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& Ono, S
