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Deletion of glutathione biosynthesis genes in PAO1 in two separate studies have linked glutathione to the increased production of virulence factors like pyocyanin and persister cell formation, however they reported conflicting results about glutathiones effect on increasing or reducing biofilm formation (38, 39)

While Figures 1, 2 summarize ASTs modulation of oxidative and inflammatory pathways, it is important to note that these models are derived largely from preclinical studies

Briefly, the mixture solution of 99 ml H 2 O and 1 ml HAuCl 4 (1%) is uniform under stirring, then heated to be boiling

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